The government’s focus on expanding cancer treatment centers and facilitating access to modern therapeutics are fostering market development. The presence of international pharmaceutical companies and ongoing research collaborations further enhance treatment options. As the healthcare system continues to evolve, Sri Lanka is positioning itself as a key player in regional cancer management, with an emphasis on innovative therapies and patient-centric care models. Indonesia’s pancreatic and bile duct cancer drug market is anticipated to expand rapidly, driven by increasing disease awareness and a burgeoning healthcare sector. Government initiatives aimed at improving cancer screening and treatment infrastructure are pivotal. The rising prevalence of risk factors such as smoking and obesity contributes to higher cancer incidence.
Characteristics of Commodities
The crawler was implemented in Python and used the Selenium module to launch browsers and to send crawling requests [24]. To avoid blocking from the marketplace, we provided as an input to the scraper a session cookie that we obtained by manually logging into the marketplace and solving a Completely Automated Public Turing test to tell Computers and Humans Apart (CAPTCHA). However, some sites, namely, the Empire Market, forced users to log out when the life span of the session cookie was expired.
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A hurricane came through our area, our rep actually delivered our order in his vehicle when delivery trucks couldn’t get through. He made sure that all of his stores had what they needed to stay open and serve customers. Our merchandisers and pharmacy experts can maximize your success as a business owner. Whether its guidance on setting up the front end or information on new offerings and products, our customers regularly share feedback on what a difference our team has made to their store.
Torque Motor Rotary Tables Market Emerging Trends and Evolving Dynamics Indonesia Pakistan Sri Lanka Vietnam
As observed in our data set, the top 3 marketplaces with the most opioid listings are Agora, Evolution, and Apollon. Our study identified 41,000 opioid trade–related marketplace listings and forum posts by analyzing more than 1 million listings and posts in multiple anonymous marketplaces and forums, which is the largest underground opioid trading data set ever reported. We found evidence through extensive analyses of the anonymous online market of pervasive supply, which fuels the international opioid epidemic. Nontraditional methods, as presented here by studying the online supply chain, present a novel approach for governmental and other large-scale solutions.
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- Addressing this challenge requires deep domain knowledge and expertise, which is constantly evolving.
- Emerging markets are showing promising potential due to improving healthcare infrastructure and heightened awareness.
- In fact, the shutdown of the marketplace Evolution was discovered to be an exit scam, with the site’s operators shutting down abruptly to steal the approximately US $12 million in bitcoins that it was holding as an escrow [39].
- Unlike traditional marketplaces with shared backup mirrors, our system provides truly unique onion addresses for enhanced security and reliability.
- Welcome to Drughub Market, the premierdarknet platform crafted by the esteemed White House Market team, operatingsecurely for over 2 years.
- Mackey et al [13] collected tweets related to the opioid topic to identify illicit online pharmacies and study the illegal sale of opioids in online marketing.
- Note that some high-profile underground marketplaces and forums are frequently deactivated or have been shut down by law enforcement authorities [23].
In addition to the engineering controls to prevent contamination, LOTTE Biologics employs a combination of operational controls and monitoring. This involves robust cleaning and product changeover procedures, as well as gowning and material flow protocols, Yourd said. The .gov means it’s official.Federal government websites often end in .gov or .mil.
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Infrastructure development, manufacturing expansion, and technology adoption offer strong opportunities. This is a dangerous line of work – you’ll have to contend with increasing law enforcement, as well as deadly cartel competitors. In addition to strong quality processes to support consistent global compliance, LOTTE Biologics has robust regulatory and compendium surveillance, Yourd said. This is a group of scientists, quality assurance employees, and other departments that track global regulatory trends and upcoming revisions to regulatory guidances, as well as compendial updates for aspects like material testing, she added.
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is the regularization term, which is the L1-norm.
Underground Opioid Trading
We then identified 311 opioid keywords and jargons to recognize 28,106 listings and 13,508 forum traces related to underground opioid trading activities. Finally, we used natural language processing techniques to extract opioid trading information to characterize underground opioid commodities, suppliers, and transactions. We aimed to profile the opioid supply chain in anonymous markets and forums via a large-scale, longitudinal measurement study on anonymous market listings and posts. Toward this, we propose a series of techniques to collect data; identify opioid jargon terms used in the anonymous marketplaces and forums; and profile the opioid commodities, suppliers, and transactions. We trained the semantic comparison model using the traces of Reddit as the benign corpora and the traces of the anonymous marketplaces/forums as the underground corpora.
Real people.Real results.
Market growth is further supported by international collaborations and investments in healthcare technology. The focus on improving access to innovative therapies and expanding clinical research activities positions Indonesia as a promising emerging market for pancreatic and bile duct cancer treatments. Anonymous online marketplaces are usually platforms for sellers and buyers to conduct transactions in a virtual environment.
Indonesia Pancreatic And Bile Duct Cancer Market data and reports
- Our commitment to quality research and client success has established us as a trusted name in global market intelligence.
- This is a group of scientists, quality assurance employees, and other departments that track global regulatory trends and upcoming revisions to regulatory guidances, as well as compendial updates for aspects like material testing, she added.
- Note that we should not overestimate the number of suppliers and buyers given the number of IDs found in this research, but we regarded it as the upper-bounded number of the opioid suppliers and buyers.
- To participate in the 340B Program, eligible organizations/covered entities must register and be enrolled with the 340B program and comply with all 340B Program requirements.
- Owing to the anonymity of the underground marketplaces and forums, there exists no ground truth to link users with their IDs.
- Authorities are now combing through the establishment’s “clientele” to distinguish between those visiting for a souvlaki and those seeking illicit substances.
- We present a view about how such services operate and how different entities interact with each other (Figure 1).
- According to police, the trio faces charges of possession and trafficking across Athens and Piraeus.
- Dasgupta et al [18] collected opioid listings on Silk Road to analyze the prices of diverted prescription opioids.
Increasing awareness campaigns and government support for cancer management initiatives are key contributors. The expanding pharmaceutical sector and international partnerships are facilitating access to innovative therapies. Challenges such as limited healthcare resources are being addressed through policy reforms and investments in diagnostic facilities. The focus on expanding treatment options and clinical research is expected to accelerate market growth, making Pakistan an emerging hub for pancreatic and bile duct cancer therapeutics in the region. Sri Lanka’s pancreatic and bile duct cancer drug market is expected to grow steadily, supported by increased healthcare spending and improved diagnostic capabilities. Rising awareness about cancer symptoms and early detection programs are crucial factors.
We pride ourselves on relationships that have lasted generations because they are built on trust and transparency, but we aren’t satisfied to rest on past success. We define ourselves by the service we provide, the solutions we bring to your pharmacy and the trust you place in us. Administered by seasoned experts, pen-tested by top security specialists,with industry-leading protections like END GAME DDoS filter. Funds are automatically transferred to our secure escrow system, protectingboth buyer and vendor interests. Secure escrow system holds funds for 7-21 days depending on productcategory, with automatic release upon delivery confirmation or disputeresolution through our moderation team. All communications and sensitive data are protected using Pretty GoodPrivacy (PGP) encryption with 4096-bit keys, ensuring complete privacy fromthird-party interception.
Authorities also found heat sealers, repackaging tools, and a collection of imported cannabis-laced products, including vape pens, edibles, and live resin. Food delivery boxes were also discovered, allegedly used to move the drugs discreetly. In a statement, the National Bureau of Investigation Southeastern Mindanao Regional Office (NBI SEMRO XI) said the operation took place in a subdivision where the suspects had allegedly turned a quiet home into a full-scale drug hub. At Market Research Intellect, our mission is to bridge the gap between data and decision-making. We partner with organizations of all sizes—from startups to Fortune 500 companies—to help them optimize strategies, strengthen competitiveness, and drive sustainable growth.
- The Pakistani market for pancreatic and bile duct cancer drugs is poised for growth, driven by rising cancer prevalence and improving healthcare infrastructure.
- To this end, we first collected the marketplace’s lifespan using the Gwern archive [37], as shown in Table 1, and then compared the supplier lists in each marketplace to investigate supplier migration.
- International collaborations and investments in healthcare technology are fostering innovation and market development.
- A hurricane came through our area, our rep actually delivered our order in his vehicle when delivery trucks couldn’t get through.
- The Vietnamese market for pancreatic and bile duct cancer drugs is projected to grow steadily over the next five years, driven by increasing healthcare investments and rising awareness about early diagnosis.
- First Longevity Limited does not give advice on the risks of investment and is not authorised to carry out investment business under the Financial Services and Markets Act 2000 (“FSMA”).
- Most recently, Swiss pharma behemoth Novartis unveiled plans to build a new radioligand therapy manufacturing facility in Winter Park, Florida, as part of a $23 billion U.S. investment pledge announced in April 2025.
- For example, there might be varying types of heroin or fentanyl, but we could not subcategorize them due to the lack of precise ontology.
We found that 182 opioid supplier IDs appeared in both the marketplaces Evolution and Agora from January 2014 to July 2015. In particular, we observed that 84 opioid supplier IDs synchronized similar product listings in both marketplaces at the same time. This might be because the suppliers tend to promote their products across various marketplaces and to increase sales. Note that we should not overestimate the number of suppliers and buyers given the number of IDs found in this research, but we regarded it as the upper-bounded number of the opioid suppliers and buyers.
Hence, we also gathered snapshots of 5 underground marketplaces and 6 forums collected by the anonymous marketplace archives programs and previous research projects [20]. We first conducted a whole-site crawl of anonymous online marketplaces and forums to solicit data. Anonymous online marketplaces and forums usually operate as hidden Tor services, which can only be resolved through Tor (an anonymity network). Figures 2 and 3 illustrate examples of opioid listings in The Versus Project and Alphabay.
P23 million worth of drugs seized from delivery hub disguised as home in Davao City
We observed the same listings posted in different marketplaces and illustrate the dependency of the same opioid listings among different marketplaces. Note that we determined if 2 listings are identical by matching the same elements (ie, listing’s title and description information and the vendor’s name) in 2 listings. We observed that the marketplaces of Agora and Evolution shared 530 opioid listings from 290 unique supplier IDs. The opioid commodity with most listings across different marketplaces was #4 White Vietnamese Heroin, which can be found in the marketplaces Agora, Evolution, Hydra, and Pandora. To collect the listing information of 5 anonymous online marketplaces (ie, Apollon, Avaris, Darkbay, Empire, and The Versus Project), we conducted a whole-site crawl.
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In particular, in the semantic comparison model, the size of the input layer was doubled while not expanding either the hidden or the output layer. Hence, every word has 2 vectors, each describing the word’s relations with other words in one corpus. In the meantime, these 2 vectors are still comparable because they are used together in the neural network to train a single skip-gram model for predicting the surrounding windows of context words. The Pakistani market for pancreatic and bile duct cancer drugs is poised for growth, driven by rising cancer prevalence and improving healthcare infrastructure.
- To evaluate the aforementioned methods for extracting properties, we randomly chose 1000 listings for each property and manually annotated the properties as ground truth.
- The company already employs more than 20,000 people, and operates over 480 facilities across 26 countries, integrating genomics, biobanks, digital health data and AI technologies to deliver predictive, personalized healthcare.
- After perusing the items available on the anonymous online market (step 5), the buyer will add opioids to their shopping cart (step 6).
- In fact, the shutdown of the marketplace Evolution was discovered to be an exit scam, with the site’s operators shutting down abruptly to steal the approximately US $12 million in bitcoins that it was holding as an escrow [39].
- Note that some high-profile underground marketplaces and forums are frequently deactivated or have been shut down by law enforcement authorities [23].
- Welcome to Drughub Market, the premierdarknet platform crafted by the esteemed White House Market team, operatingsecurely for over 2 years.
- The Pancreatic And Bile Duct Cancer Drug Market refers to the global industry involved in the development, production, and deployment of Pancreatic And Bile Duct Cancer Drug solutions across various end-use sectors.
Attorney Thomas Huyck has joined Foster Swift’s healthcare and business practice groups
Additionally, DrugHub provides vendors with access to private mirrors, adding an extra layer of security against unauthorized access. Note that data for 2020 only included data from January to March; price per gram is in US $. Each year, Frost & Sullivan presents this award to the company that has developed a product with innovative features and functionality that is gaining rapid acceptance in the market. The award recognizes the quality of the solution and the customer value enhancements it enables. M&A activities help companies expand capabilities, market reach, and competitive positioning.
These neighborhood hubs serve as meeting points where people of all ages and backgrounds gather for a quick, affordable, and deeply satisfying meal. According to police, the trio faces charges of possession and trafficking across Athens and Piraeus. During raids on homes and the shop, officers seized 280 grams (9.9 oz) of heroin, 18 grams (0.64 oz) of cocaine, 51.5 grams (1.8 oz) of cannabis, and €12,480 (about $14,880) in cash.
Never access Drug Hub or any darknet marketplace without proper security precautions. Always use Tor Browser with security level set to “Safest.” Encrypt all sensitive communications with PGP. Longevity biotech Juvenescence today announced the first close of its Series B-1 financing round, securing $76 million to support the continued development of its AI-driven clinical pipeline focused on age-related diseases. The round was led by M42, a tech-enabled healthcare company headquartered in Abu Dhabi, with additional participation from existing investors. The full close of the financing round is expected in the third quarter of this year, with the company reportedly aiming to raise more than $150 million in total.
The results show that vendors’ trustworthiness is a better predictor of vendor selection than product diversity or affordability. Considering social media data (eg, Twitter and Instagram), Nasralah et al [14] proposed a text mining framework to collect opioid data from social media and analyzed the most discussed topics to profile the opioid epidemic and crisis. Mackey et al [13] collected tweets related to the opioid topic to identify illicit online pharmacies and study the illegal sale of opioids in online marketing. Cherian et al [12] gathered codeine misuse data from Instagram posts to understand how misuse is happening and its misused form. To the best of our knowledge, a comprehensive overview of the opioid supply chain in the anonymous online marketplaces and forums, as well as a measurement study of trading activities, is still an open research challenge. This is the first study to measure and characterize opioid trading in anonymous online marketplaces and forums.
Third, we conducted a comprehensive, large-scale, longitudinal study to measure and characterize opioid trading in anonymous online marketplaces and forums. In our study, a total of 248,359 listings from 10 anonymous online marketplaces and 1,138,961 traces (ie, threads of posts) from 6 underground forums were collected. Among them, we identified 28,106 opioid product listings and 13,508 opioid-related promotional and review forum traces from 5147 unique opioid suppliers’ IDs and 2778 unique opioid buyers’ IDs.
When interpreted by professionals, our initial results demonstrate useful findings and may be used downstream by law enforcement and public policy makers for impactful structural interventions to the opioid crisis. Although a large body of current research is focused on pathways for treatment of opioid use disorder and analyzing deaths per treatment capacity of substance use providers, these research areas are limited to the demand side of the opioid epidemic [40,41]. We believe that the findings and pattern analyses presented here, which place concentration on the supply side, might suggest a new direction to focus and will serve as a useful complement to current research conducted within the domain of addiction medicine. This section elaborates on the methodology used to identify opioid trading information in the anonymous market and forums. Specifically, we collected approximately 248,359 unique listings and 1,138,961 unique forum traces (ie, threads of posts) from 10 anonymous online marketplaces and 6 forums.
In early 2025, the company broke ground on a $2 billion manufacturing facility project in Wilson. The drugmaker followed that up with a $2 billion deal in September for manufacturing space at Fujifilm Biotechnologies’ Holly Springs location. It also recently announced plans to build a second multibillion-dollar facility in Wilson. I am probably one of Smith Drug Company’s best advocates because of their customer service. There were multiple shortages on our shipments; Smith Drug Company was able to step in and get us what we needed in a timely fashion.
This onion is protected by custom sophisticated CAPTCHA systems and POWenabled to give you the best experience using DrugHub market. This said… at this point in time I would not be surprised if DrugHub has been had it’s servers imaged by Law Enforcement and investigations at this point are probably underway. Drug Hub operates a private Jabber server for push notifications and optional vendor communication. Configure your Jabber client with provided credentials to receive instant alerts.
Particularly, as shown in Table 8, the United States and the United Kingdom are always in the top 5 advertised origins among years. We compared our method with the state-of-the-art topic modeling method Machine Learning for Language Toolkit (MALLET) [30] and our model without transfer learning stage (baseline). In particular, MALLET is retrained and evaluated via 10-fold cross-validation. drughub.su We also applied the MALLET topic modeling toolkit (package cc.mallet.topics MALLET’s class in JavaDoc API) on the same data set to predict the type of topic. The baseline model was applied directly to the labeled data (Table 3) and evaluated using 10-fold cross-validation. We used the metrics of precision and recall to compare the performance of different topic modeling methods.
Find our official onion link and verified mirror here to access ourmarketplace for an unparalleled, private browsing experience. This finding is roughly in line with the observation of 57 opioid vendors’ origin in a marketplace named Cryptomarket during the period of October 2015 through April 2016, which was reported by Duxbury et al [6]. In addition, we did not observe big changes in the top opioid commodity origins from 2014 to 2020.
